DONOR PROGRAMME

  • ABOUT

A embryo is formed with fertilization of an egg and a sperm.

This treatment is needed in many conditions like :

  • Advanced age
  • Premature Ovarian failure or reproductive ageing
  • Decreasing ovarian reserve
  • Recurrent IVF failures due to poor oocyte quality
  • Risk of genetic disease transmission in offspring

Even with ART treatment, women’s eggs are not capable of forming a healthy embryo which can give rise to pregnancy. In such conditions, donor egg is one of the treatment options offered.

If above condition is associated with Azoospermia (sperms not retrieved surgically) or genetic abnormality in male partner, along with donor egg, donor sperm may also be used.

  • WHO ARE EGG DONORS?

Young women of age group of 20-30.

Known fertility potential (Having their own genetically normal child within last 5 years).

Not having any genetic disease or child affected with genetic disease.

No history of recurrent miscarriage.

No major medical or surgical illness.

No addiction

  • HOW IS THE EGG DONOR SELECTED AND SCREENED?
  • Detailed case history and examination of donor is done :
  • Age/ Marital status/ Education/ Occupation
  • Menstrual and Obstetric history
  • Family history (history of any genetic/congenital abnormalities in any family member)
  • Personal history (habits like using tobacco, smoking, drinking, what is the contraceptive being used)
  • Detailed systemic examination
  • Assessment of her Ovarian Reserve :
  • Donor’s ovarian reserve is assessed with her blood AMH (Anti-Mullerian Hormone level) and her AFC count (Antral follicle count) seen on Ultrasonography.
  • Assessment of her Ovarian Reserve :
  • Routine tests- Hemogram and blood grouping
  • Infection screening- HIV, HBsAg, VDRL, HCV
  • Hormone profile- S.TSH
  • Hb Electrophoresis
  • Liver function test
  • Renal function test
  • Optional- Karyotyping
  • After matching the requirements, the donor is recruited.
  • PROCEDURE
  • Matching with donor.
  • Synchronization of menses of donor and recipient.
  • Controlled ovarian hyperstimulation of donor.
  • Recipient’s treatment to prepare the endometrium for implantation.
  • Oocyte retrieval from the donor.
  • In vitro Fertilization of retrieved oocytes with the recipient’s husband’s sperm /Donor sperm obtained from Sperm bank
  • Culture of embryos.
  • Embryo transfer in recipient’s uterus and luteal phase support.
  • Serum beta HCG level on day 14.
  • SUCCESS RATE

As compared to the success rate of IVF with your own eggs, success rates with donor eggs and embryos are considerably high to the tune of 50-60%.

There are no problems associated with pregnancy after oocyte or embryo donation.

  • OOCYTE, SEMEN AND EMBRYO FREEZING

There are many couples or single individuals, who would wish to preserve their fertility potential (which decreases with age) and plan for family at a later stage.

This could be people with professional or personal reasons. This could also be people unfortunately affected by cancer before finishing their reproductive life.

These individuals could opt for semen or egg freezing or the couple could opt for embryo freezing (embryo is formed using wife’s egg and husband’s sperm).

These freezing techniques provide time to the couples for accomplishing their desires and at the same time keeps the window of possibility open for them to become parents at a bit delayed stage of their life.